(Re)pensar sobre as Cidades Contemporâneas: Contribuições ao Debate

As cidades de hoje são diferentes das cidades do passado. Tornaram-se mais complexas, mais densas e com vários problemas em comum, como é o caso dos resíduos sólidos urbanos, mobilidade urbana e da sustentabilidade ambiental, por exemplo. As necessidades dos cidadãos são diversas, mas similares a inúmeras outras cidades no mundo todo. O viver em uma cidade estabelece relações com o urbano e com a natureza, bem como pressupõe a existência do que Raffestin (1993) chamou de território vivido em contraste com o que Pecqueur (2005) denominou de território dado. A cidade é um espaço multifacetado por outros territórios que muitas vezes se sobrepõem. Outras vezes contrastam e disputam espaço (físico e simbólico), o que lhes proporciona um diálogo urbano por meio de seus conflitos, parcerias e relações que estabelece entre si e com o meio ambiente.As cidades têm sido foco de discussões globais, como: sustentabilidade, planejamento urbano, moradias para pessoas de baixa renda, periferia, conflito e parcerias entre atores sociais, identidade territorial e cultural, densidade, população, mobilidade, inteligência das cidades, cidades digitais e estratégicas, cidades virtuais, marcas de cidades, imagem da cidade, fluxos, migrações, energia sustentável. A cada marco temporal os espaços urbanos vão se redescobrindo e se reinventando, levando a novos usos e apropriações, bem como conflitando ou corroborando com a pluralidade de discursos e práticas que lhe abarcam cotidianamente

The relationship between Unions and Innovation in Chile

This article examines how and to what extent unions affect companies’ innovation in Chile. It contributes to the existing literature in the following two aspects: First, because it widens the scope of analysis focusing in a developing country that is characterized by some specificities regarding the innovation as well the union landscape. Second, because it provides more in-depth analysis, taking into account the effect of unions on the four different types of innovation proposed in the Oslo Manual by OECD. Results show that unions do not affect product and process innovation while influence organizational innovation and marketing in a non-linear wa

Deep Learning for Predicting Congestive Heart Failure

Congestive heart failure (CHF) is one of the most debilitating cardiac disorders. It is a costly disease in terms of both lives and financial outlays, given the high rate of hospital re-admissions and mortality. Heart failure (HF) is notoriously difficult to identify on time, and is frequently accompanied by additional comorbidities that further complicate diagnosis. Many decision support systems (DSS) have been developed to facilitate diagnosis and to raise the standard of screening and monitoring operations, even for non-expert staff. This is confirmed in the literature by records of highly performing diagnosis-aid systems, which are unfortunately not very relevant to expert cardiologists. In order to assist cardiologists in predicting the trajectory of HF, we propose a deep learning-based system which predicts severity of disease progression by employing medical patient history. We tested the accuracy of four models on a labeled dataset, composed of 1037 records, to predict CHF severity and progression, achieving results comparable to studies based on much larger datasets, none of which used longitudinal multi-class prediction. The main contribution of this work is that it demonstrates that a fairly complicated approach can achieve good results on a medium size dataset, providing a reasonably accurate means of determining the evolution of CHF well in advance. This potentially constitutes a significant aid for healthcare managers and expert cardiologists in designing different therapies for medication, healthy lifestyle changes and quality of life (QoL) management, while also promoting allocation of resources with an evidence-based approach. © 2022 by the authors

Postambulatory Hand Swelling (Big Hand Syndrome): Prevalence, Demographics, and Association with Dog Walking

Introduction. Postambulatory hand swelling (PAHS) seems to be common in the general population. There are few mention in the medical literature. The objective were (1) to identify prevalence; (2) to compare gender and age groups; (3) to determine if dog owners and walkers are more or less prone. Materials and Methods. 1009 semirandomly surveys were completed from walkers. Age, gender, and dog ownership were assessed. We discussed, among dog owners, whether or not they walk their dog regularly, whether or not they notice swollen hands after walking, and, if so, if the swelling resolves over 24 hours or persists. Results. 699 females and 410 males, among whom, 28.9% of females but only 16.3% of males reported PAHS (P < 0.001). Surprisingly, those with swelling were statistically younger than those without (49.2 versus 52.8 years, P = 0.003), and dog owners were more likely than nonowners to report swelling (28.1% versus 21.7%; P = 0.015). In terms of persistent swelling, this was observed in twice the percentage of females as males (13.3 versus 6.5%) and tended to involve older subjects (54.0 versus 48.8 years), but with no statistical difference significance. Conclusions. PAHS is a relatively common phenomenon, seemingly more common in females

The Borexino Thermal Monitoring & Management System and simulations of the fluid-dynamics of the Borexino detector under asymmetrical, changing boundary conditions

A comprehensive monitoring system for the thermal environment inside the Borexino neutrino detector was developed and installed in order to reduce uncertainties in determining temperatures throughout the detector. A complementary thermal management system limits undesirable thermal couplings between the environment and Borexino's active sections. This strategy is bringing improved radioactive background conditions to the region of interest for the physics signal thanks to reduced fluid mixing induced in the liquid scintillator. Although fluid-dynamical equilibrium has not yet been fully reached, and thermal fine-tuning is possible, the system has proven extremely effective at stabilizing the detector's thermal conditions while offering precise insights into its mechanisms of internal thermal transport. Furthermore, a Computational Fluid-Dynamics analysis has been performed, based on the empirical measurements provided by the thermal monitoring system, and providing information into present and future thermal trends. A two-dimensional modeling approach was implemented in order to achieve a proper understanding of the thermal and fluid-dynamics in Borexino. It was optimized for different regions and periods of interest, focusing on the most critical effects that were identified as influencing background concentrations. Literature experimental case studies were reproduced to benchmark the method and settings, and a Borexino-specific benchmark was implemented in order to validate the modeling approach for thermal transport. Finally, fully-convective models were applied to understand general and specific fluid motions impacting the detector's Active Volume.Comment: arXiv admin note: substantial text overlap with arXiv:1705.09078, arXiv:1705.0965

Le nouveau cirque américain

On peut dire que depuis ses débuts, vers les 1870, le cirque américain a connu des périodes où il aspirait au grand art et où il empruntait au théâtre des artistes, des techniques et la dramaturgie. Ce n’est qu’en 1975, lorsque des artistes ont abandonné l’idéal américain de la grandeur pour adopter le modèle européen de la piste simple que ce mouvement a connu son véritable essor. Le Big Apple Circus, le Pickle Family Circus, le Cirque du Soleil et Circus Flora ont réussi à théâtralisé le cirque américain. Même le géant du cirque à trois pistes, le Ringling Bros. and Barnum & Bailey, a commencé à donner à ses spectacles une allure plus théâtrale. Le Midnight Circus, Circus Sarasota ainsi que Barnum’s Kaleidoscape, entre autres, ont continué à trouver de nouvelles façons d’allier le cirque et le théâtre. Des écoles de cirque ont été fondées afin de fournir aux nouveaux cirques des artistes formés aux nouvelles techniques. Tous visent à faire évoluer le cirque vers la forme d’art à laquelle il a toujours aspiré.Almost from its very beginning, in the 1870's, the American circus has gone through periods when it aspired to high art and borrowed artists, techniques and dramaturgy from the theatre. It was not until 1975, when certain artists abandoned the all-American ideal that bigger was always better and opted, instead, to model their new circuses after the European model of the one ring circus, that this movement began to gain momentum. The Big Apple Circus, The Pickle Family Circus, Cirque du Soleil, and Circus Flora were leaders in the movement to theatricalize the American circus. Eventually even the three-ring giant, Ringling Bros. and Barnum & Bailey, began to refashion its performance in a more theatrical manner. These early circuses were followed by the Midnight Circus, Circus Sarasota and Barnum's Kaleidoscape, among others, which continued to find new ways of melding circus and theatre. To provide performing artists for these new circuses, new circus schools had to be founded to train the artists in the new style and technique demanded by the new circuses. Together the artists and the various circuses are seeking to have the circus evolve into the unique art form it has always hoped to be

Patients with paediatric-onset multiple sclerosis are at higher risk of cognitive impairment in adulthood: an Italian collaborative study

Background: Patients with paediatric-onset multiple sclerosis (POMS) could be at an increased risk for cognitive impairment (CI), given the potential harmful effects of disease activity in neurodevelopment. However, there is scarce information on their long-term cognitive outcomes. Objective: To compare the prevalence and profile of CI between adults with a history of POMS and those with classic, adult-onset multiple sclerosis (AOMS). Methods: Cognitive performance was assessed through the Brief Repeatable Battery (BRB) and the Stroop Test in consecutive patients referred to six Italian MS centres. CI was defined as impairment in ⩾2 cognitive domains. Results: In all, 119 patients with POMS and 712 with AOMS were included in this analysis. The prevalence of CI was 48.0% in AOMS, 44.5% in POMS; with similar neuropsychological profile between the two groups. However, when adjusting for current age, we found a significantly increased risk for CI (odds ratio (OR) = 1.71; p = 0.02) and for impairment in information processing speed (OR = 1.86; p < 0.01) in patients with POMS. A higher Expanded Disability Status Scale (EDSS) was also identified in POMS (p = 0.03) compared with AOMS patients.The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: This study was in part financed through an FISM (Italian Federation of Multiple Sclerosis) research grant

Relevance of brain lesion location to cognition in relapsing multiple sclerosis

OBJECTIVE: To assess the relationship between cognition and brain white matter (WM) lesion distribution and frequency in patients with relapsing-remitting multiple sclerosis (RR MS). METHODS: MRI-based T2 lesion probability map (LPM) was used to assess the relevance of brain lesion location for cognitive impairment in a group of 142 consecutive patients with RRMS. Significance of voxelwise analyses was p<0.05, cluster-corrected for multiple comparisons. The Rao Brief Repeatable Battery was administered at the time of brain MRI to categorize the MS population into cognitively preserved (CP) and cognitively impaired (CI). RESULTS: Out of 142 RRMS, 106 were classified as CP and 36 as CI. Although the CI group had greater WM lesion volume than the CP group (p = 0.001), T2 lesions tended to be less widespread across the WM. The peak of lesion frequency was almost twice higher in CI (61% in the forceps major) than in CP patients (37% in the posterior corona radiata). The voxelwise analysis confirmed that lesion frequency was higher in CI than in CP patients with significant bilateral clusters in the forceps major and in the splenium of the corpus callosum (p<0.05, corrected). Low scores of the Symbol Digit Modalities Test correlated with higher lesion frequency in these WM regions. CONCLUSIONS: Overall these results suggest that in MS patients, areas relevant for cognition lie mostly in the commissural fiber tracts. This supports the notion of a functional (multiple) disconnection between grey matter structures, secondary to damage located in specific WM areas, as one of the most important mechanisms leading to cognitive impairment in MS

The Nylon Scintillator Containment Vessels for the Borexino Solar Neutrino Experiment

Borexino is a solar neutrino experiment designed to observe the 0.86 MeV Be-7 neutrinos emitted in the pp cycle of the sun. Neutrinos will be detected by their elastic scattering on electrons in 100 tons of liquid scintillator. The neutrino event rate in the scintillator is expected to be low (~0.35 events per day per ton), and the signals will be at energies below 1.5 MeV, where background from natural radioactivity is prominent. Scintillation light produced by the recoil electrons is observed by an array of 2240 photomultiplier tubes. Because of the intrinsic radioactive contaminants in these PMTs, the liquid scintillator is shielded from them by a thick barrier of buffer fluid. A spherical vessel made of thin nylon film contains the scintillator, separating it from the surrounding buffer. The buffer region itself is divided into two concentric shells by a second nylon vessel in order to prevent inward diffusion of radon atoms. The radioactive background requirements for Borexino are challenging to meet, especially for the scintillator and these nylon vessels. Besides meeting requirements for low radioactivity, the nylon vessels must also satisfy requirements for mechanical, optical, and chemical properties. The present paper describes the research and development, construction, and installation of the nylon vessels for the Borexino experiment